Yes! Once you set up domain-wide delegation, you can add a list of mailboxes as additional targets and batch-create their acquisition projects. You can then start/resume those using the supplied batch file, or split them up and run them on multiple computers in parallel.
We have some more info on this here:
This also applies to regular acquisitions without delegation (e.g., Yahoo). In that case, you would need to include passwords for each additional target in your target list file.
We also have a quick walkthrough of this in the last webinar recording here (minute 43):